mouse CXADR shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Cxadr

Gene Name

coxsackie virus and adenovirus receptor

Gene ID

13052

Gene Synonyms

2610206D03Rik; AU016810; AW553441; CAR; MCAR; MCVADR

ORF Size

1059 bp

RefSeq#

NM_009988

Gene Description

Component of the epithelial apical junction complex that is essential for the tight junction integrity. Proposed to function as a homophilic cell adhesion molecule. Recruits MPDZ to intercellular contact sites. Probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN.

UniGene ID

Mm.66222