mouse MAP3K2 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Map3k2

Gene Name

mitogen-activated protein kinase kinase kinase 2

Gene ID

26405

Gene Synonyms

9630061B06Rik; AI585793; Mekk2; Mekk2b

ORF Size

1860 bp

RefSeq#

NM_011946

Gene Description

Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.

UniGene ID

Mm.211762