human GUCY1A3 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GUCY1A3

Gene Name

guanylate cyclase 1 soluble subunit alpha

Gene ID

2982

Gene Synonyms

GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1; MYMY6

ORF Size

2073 bp

RefSeq#

NM_000856

Gene Description

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

UniGene ID

Hs.24258

HGNC ID

HGNC:4685