human PI4K2B shRNA silencing AAV

Cat. No: shAAV-229442

Availability: 4-5 weeks

Name: AAV-h-PI4K2B-shRNA

This is an AAV expressing shRNA for silencing of Human PI4K2B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PI4K2B
Gene Name: phosphatidylinositol 4-kinase type 2 beta
Gene ID: 55300
Gene Synonyms: PI4KIIB; PIK42B
ORF Size: 1446 bp
RefSeq#: NM_018323
Gene Description: Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate (PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 (PubMed 12324459)).(supplied by OMIM, Jun 2008)
UniGene ID: Hs.191701
HGNC ID: HGNC:18215