human SUV39H1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SUV39H1

Gene Name

suppressor of variegation 3-9 homolog 1

Gene ID

6839

Gene Synonyms

H3-K9-HMTase 1; KMT1A; MG44; SUV39H

ORF Size

1239 bp

RefSeq#

NM_003173

Gene Description

SUV39H1 is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.

UniGene ID

Hs.522639

HGNC ID

HGNC:11479