human C19ORF2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

URI1

Gene Name

chromosome 19 open reading frame 2

Gene ID

8725

Gene Synonyms

FLJ10575; NNX3; RMP; URI; C19ORF2;

ORF Size

1485 bp

RefSeq#

NM_003796

Gene Description

URI1 encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. URI1 may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22.

UniGene ID

Hs.466391

HGNC ID

HGNC:13236