human EIF3M shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF3M

Gene Name

eukaryotic translation initiation factor 3 subunit M

Gene ID

10480

Gene Synonyms

B5; GA17; hfl-B5; PCID1; TANGO7

ORF Size

1125 bp

RefSeq#

NM_006360

Gene Description

EIF3M encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome.

UniGene ID

Hs.502244

HGNC ID

HGNC:24460