human USP21 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

USP21

Gene Name

ubiquitin specific peptidase 21

Gene ID

27005

Gene Synonyms

USP16; USP23

ORF Size

1698 bp

RefSeq#

NM_012475

Gene Description

USP21 encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. USP21 has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

UniGene ID

Hs.8015

HGNC ID

HGNC:12620