mouse TLE1 Over-expression AAV

Name 
AAV-m-TLE1
Cat No 
AAV-274259
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tle1.

AAV-274259
AAV-m-TLE1

Ready-to-use AAV expressing Mouse Tle1 (transducin-like enhancer of split 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C230057C06Rik; Estm14; Grg-1; Grg1; Tle4l
Description (Vector)
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Gene ID
21885
Gene Name (Vector)
transducin-like enhancer of split 1
Gene Symbol
Tle1
ORF Size (aa)
2310
ORF Size (bp)
2310 bp
RefSeq ID
NM_011599
RefSeq Synonyms
NM_011599, NM_001285532, NM_001285531, NM_001285530, NM_001285529, BC057573,
Species
mouse
UniGene ID
Mm.399716

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.