human TLE1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TLE1.
shAAV-225562
AAV-h-TLE1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TLE1 (transducin like enhancer of split 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E(Sp1) homolog; enhancer of split groucho-like protein 1; ESG; ESG1; GRG1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer protein 1
Description (eCommerce)
transducin-like enhancer protein 1 (TLE1) is a transcriptional corepressor that binds to a number of transcription factors. TLE1 Inhibits NF-kappa-B-regulated gene expression and inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q04724].
Gene ID
7088
Gene Name (eCommerce)
transducin like enhancer of split 1
Gene Name (Vector)
transducin like enhancer of split 1
Gene Symbol
TLE1
HGNC ID
HGNC:11837
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2313
ORF Size (bp)
2313 bp
Protein Name (eCommerce)
Transducin-like enhancer protein 1
RefSeq ID
NM_005077
RefSeq Synonyms
NM_005077, NM_001303104, NM_001303103, BC015747, BC010100,
Research Areas
Cancer,Gene Expression,NF-kB Signaling,Notch Signaling,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
transducin-like enhancer protein 1 (TLE1) is a transcriptional corepressor that binds to a number of transcription factors. TLE1 Inhibits NF-kappa-B-regulated gene expression and inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q04724].
UniGene ID
Hs.689805
UniProt ID (eCommerce)
Q04724
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.