mouse TLE1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tle1.
shAAV-274259
AAV-m-TLE1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tle1 (transducin-like enhancer of split 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C230057C06Rik; Estm14; Grg-1; Grg1; Tle4l
Description (Vector)
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Gene ID
21885
Gene Name (Vector)
transducin-like enhancer of split 1
Gene Symbol
Tle1
ORF Size (aa)
2310
ORF Size (bp)
2310 bp
RefSeq ID
NM_011599
RefSeq Synonyms
NM_011599, NM_001285532, NM_001285531, NM_001285530, NM_001285529, BC057573,
Species
mouse
UniGene ID
Mm.399716
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.