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rat RAD17 shRNA silencing Adenovirus

Name 
Ad-r-RAD17-shRNA
Cat No 
shADV-294056
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Rad17.

shADV-294056
Ad-r-RAD17-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Rad17 (RAD17 checkpoint clamp loader component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and C12orf32/RHINO onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Gene ID
310034
Gene Name (Vector)
RAD17 checkpoint clamp loader component
Gene Symbol
Rad17
ORF Size (aa)
2061
ORF Size (bp)
2061 bp
RefSeq ID
NM_001024778
RefSeq Synonyms
NM_001024778, BC098057,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.