mouse RAD17 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rad17.
shAAV-281034
AAV-m-RAD17-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rad17 (RAD17 checkpoint clamp loader component). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MmRad24
Description (Vector)
Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and C12orf32/RHINO onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Gene ID
19356
Gene Name (Vector)
RAD17 checkpoint clamp loader component
Gene Symbol
Rad17
ORF Size (aa)
2067
ORF Size (bp)
2067 bp
RefSeq ID
NM_011233
RefSeq Synonyms
NM_011233, NM_001283011, NM_001044371, BC066855,
Species
mouse
UniGene ID
Mm.248489
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.