rat PQBP1 shRNA silencing Adenovirus

Name 
Ad-r-PQBP1-shRNA
Cat No 
shADV-290086
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Pqbp1.

shADV-290086
Ad-r-PQBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Pqbp1 (polyglutamine binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
63
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
PQBP1 may suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Gene ID
302557
Gene Name (Vector)
polyglutamine binding protein 1
Gene Symbol
Pqbp1
ORF Size (aa)
792
RefSeq ID
NM_001013957
RefSeq Synonyms
NM_001013957, BC059163,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.