mouse PQBP1 shRNA silencing AAV

Name 
AAV-m-PQBP1-shRNA
Cat No 
shAAV-269280
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pqbp1.

shAAV-269280
AAV-m-PQBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pqbp1 (polyglutamine binding protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
npw38; PQBP-1; Sfc2
Description (Vector)
PQBP1 may suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Gene ID
54633
Gene Name (Vector)
polyglutamine binding protein 1
Gene Symbol
Pqbp1
ORF Size (aa)
792
RefSeq ID
NM_019478
RefSeq Synonyms
NM_019478, NM_001252529, NM_001252528, BC157976, BC051673, BC009657,
Species
mouse
UniGene ID
Mm.14616

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.