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mouse EPM2A shRNA silencing Adenovirus

Name 
Ad-m-EPM2A-shRNA
Cat No 
shADV-258592
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Epm2a.

shADV-258592
Ad-m-EPM2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Epm2a (epilepsy, progressive myoclonic epilepsy, type 2 gene alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
58
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
TcrbK)TG-BFlv; Tg(TcraK; TG-B
Description (Vector)
Dual specificity protein phosphatase. May be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules (polyglucosans). Acts as a scaffold protein to facilitate PPP1R3C/PTG ubiquitination by NHLRC1/malin. Forms a complex with NHLRC1/malin and HSP70 and this complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Isoform 2, an inactive phosphatase, could function as a dominant-negative regulator for the phosphatase activity of isoform 1.
Gene ID
13853
Gene Name (Vector)
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
Gene Symbol
Epm2a
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_010146
RefSeq Synonyms
NM_010146, BC160320,
Species
mouse
UniGene ID
Mm.89946

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.