mouse EPM2A shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-258592
Availability:
4-5 weeks
Name:
AAV-m-EPM2A-shRNA
This is an AAV expressing shRNA for silencing of Mouse Epm2a.
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Product Info
- Knockdown
- >50% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Epm2a
- Gene Name
- epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
- Gene ID
- 13853
- Gene Synonyms
- TcrbK)TG-BFlv; Tg(TcraK; TG-B
- ORF Size
- 993 bp
- RefSeq#
- NM_010146
- Gene Description
- Dual specificity protein phosphatase. May be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules (polyglucosans). Acts as a scaffold protein to facilitate PPP1R3C/PTG ubiquitination by NHLRC1/malin. Forms a complex with NHLRC1/malin and HSP70 and this complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Isoform 2, an inactive phosphatase, could function as a dominant-negative regulator for the phosphatase activity of isoform 1.
- UniGene ID
- Mm.89946
Related Products
Product | Cat No. |
---|---|
AAV-h-EPM2A | AAV-208009 |
AAV-m-EPM2A | AAV-258592 |
Ad-h-EPM2A | ADV-208009 |
Ad-m-EPM2A | ADV-258592 |
AAV-h-EPM2A-shRNA | shAAV-208009 |
Ad-h-EPM2A-shRNA | shADV-208009 |
Ad-m-EPM2A-shRNA | shADV-258592 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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