mouse EPM2A Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-258592
Availability:
3-5 weeks
Name:
AAV-m-EPM2A
This is an AAV expressing Mouse Epm2a.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Epm2a
- Gene Name
- epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
- Gene ID
- 13853
- Gene Synonyms
- TcrbK)TG-BFlv; Tg(TcraK; TG-B
- ORF Size
- 993 bp
- RefSeq#
- BC160320
- Gene Description
- Dual specificity protein phosphatase. May be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules (polyglucosans). Acts as a scaffold protein to facilitate PPP1R3C/PTG ubiquitination by NHLRC1/malin. Forms a complex with NHLRC1/malin and HSP70 and this complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Isoform 2, an inactive phosphatase, could function as a dominant-negative regulator for the phosphatase activity of isoform 1.
- UniGene ID
- Mm.89946
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