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human EPM2A shRNA silencing Adenovirus

Name 
Ad-h-EPM2A-shRNA
Cat No 
shADV-208009
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human EPM2A.

shADV-208009
Ad-h-EPM2A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EPM2A (EPM2A, laforin glucan phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EPM2; MELF
Description (Vector)
EPM2A encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.
Gene ID
7957
Gene Name (Vector)
EPM2A, laforin glucan phosphatase
Gene Symbol
EPM2A
HGNC ID
HGNC:3413
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_005670
RefSeq Synonyms
NM_005670, NM_001018041, BC070047, BC005286,
Species
human
UniGene ID
Hs.486696

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.