mouse DVL1 Over-expression AAV

Name 
AAV-m-DVL1
Cat No 
AAV-257558
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Dvl1.

AAV-257558
AAV-m-DVL1

Ready-to-use AAV expressing Mouse Dvl1 (dishevelled segment polarity protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Dvl; mKIAA4029
Description (Vector)
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Gene ID
13542
Gene Name (Vector)
dishevelled segment polarity protein 1
Gene Symbol
Dvl1
ORF Size (aa)
2088
ORF Size (bp)
2088 bp
RefSeq ID
NM_010091
RefSeq Synonyms
NM_010091, NM_001302342, BC138849, BC138848,
Species
mouse
UniGene ID
Mm.3400

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.