human DVL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human DVL1.
shADV-230740
Ad-h-DVL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human DVL1 (dishevelled segment polarity protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DRS2; DVL; DVL1L1; DVL1P1
Description (Vector)
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Gene ID
1855
Gene Name (Vector)
dishevelled segment polarity protein 1
Gene Symbol
DVL1
HGNC ID
HGNC:3084
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_004421
RefSeq Synonyms
NM_004421, NM_001330311, BC050454,
Species
human
UniGene ID
Hs.719085
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.