mouse DVL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dvl1.
shADV-257558
Ad-m-DVL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dvl1 (dishevelled segment polarity protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dvl; mKIAA4029
Description (Vector)
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
Gene ID
13542
Gene Name (Vector)
dishevelled segment polarity protein 1
Gene Symbol
Dvl1
ORF Size (aa)
2088
ORF Size (bp)
2088 bp
RefSeq ID
NM_010091
RefSeq Synonyms
NM_010091, NM_001302342, BC138849, BC138848,
Species
mouse
UniGene ID
Mm.3400
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.