human FOS Over-expression AAV

Name
AAV-h-FOS

Cat No
AAV-229259

Availability
4-5 weeks

This is an AAV expressing Human FOS.

AAV-229259

AAV-h-FOS

Ready-to-use AAV expressing Human FOS (Fos proto-oncogene, AP-1 transcription factor subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AP-1; C-FOS; p55

Description (Vector)

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Gene ID

2353

Gene Name (Vector)

Fos proto-oncogene, AP-1 transcription factor subunit

Gene Symbol

FOS

HGNC ID

HGNC:3796

ORF Size (aa)

1143

RefSeq ID

NM_005252

RefSeq Synonyms

NM_005252, BC004490,

Species

human

UniGene ID

Hs.707896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.