human FOS shRNA silencing AAV

Name 
AAV-h-FOS-shRNA
Cat No 
shAAV-229259
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FOS.

shAAV-229259
AAV-h-FOS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FOS (Fos proto-oncogene, AP-1 transcription factor subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AP-1; C-FOS; p55
Description (Vector)
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Gene ID
2353
Gene Name (Vector)
Fos proto-oncogene, AP-1 transcription factor subunit
Gene Symbol
FOS
HGNC ID
HGNC:3796
ORF Size (aa)
1143
RefSeq ID
NM_005252
RefSeq Synonyms
NM_005252, BC004490,
Species
human
UniGene ID
Hs.707896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.