human SLX1B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-229162
Availability:
3-5 weeks
Name:
AAV-h-SLX1B
This is an AAV expressing Human SLX1B.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SLX1B
- Gene Name
- SLX1 homolog B, structure-specific endonuclease subunit
- Gene ID
- 79008
- Gene Synonyms
- GIYD2
- ORF Size
- 828 bp
- RefSeq#
- BC000754
- Gene Description
- SLX1B encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
- UniGene ID
- Hs.
- HGNC ID
- HGNC:28748
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