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rat GIYD2 shRNA silencing Adenovirus

Name 
Ad-r-GIYD2-shRNA
Cat No 
shADV-292480
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Rat Slx1b.

shADV-292480
Ad-r-GIYD2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Slx1b (SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Giyd1; Giyd2; LRRGT00058; RGD1311568
Description (Vector)
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
Gene ID
293489
Gene Name (Vector)
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Gene Symbol
Slx1b
ORF Size (aa)
816
ORF Size (bp)
816 bp
RefSeq ID
NM_001009292
RefSeq Synonyms
NM_001009292, BC087090,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.