mouse GIYD2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Slx1b.
shADV-260122
Ad-m-GIYD2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Slx1b (SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110030E23Rik; 2410170E21Rik; 4833422P03Rik; AI853643; Giyd1; Giyd2
Description (Vector)
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
Gene ID
75764
Gene Name (Vector)
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Gene Symbol
Slx1b
ORF Size (aa)
813
ORF Size (bp)
813 bp
RefSeq ID
NM_029420
RefSeq Synonyms
NM_029420, BC145688,
Species
mouse
UniGene ID
Mm.280573
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.