human SLAMF6 Over-expression AAV

Name
AAV-h-SLAMF6

Cat No
AAV-223061

Availability
4-5 weeks

This is an AAV expressing Human SLAMF6.

AAV-223061

AAV-h-SLAMF6

Ready-to-use AAV expressing Human SLAMF6 (SLAM family member 6). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000

Description (Vector)

SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

114836

Gene Name (Vector)

SLAM family member 6

Gene Symbol

SLAMF6

HGNC ID

HGNC:21392

ORF Size (aa)

996

RefSeq ID

NM_052931

RefSeq Synonyms

NM_052931, NM_001184716, NM_001184715, NM_001184714, BC114495, BC113893,

Species

human

UniGene ID

Hs.492348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.