human SLAMF6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SLAMF6.
shADV-223060
Ad-h-SLAMF6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SLAMF6 (SLAM family member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000
Description (Vector)
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene ID
114836
Gene Name (Vector)
SLAM family member 6
Gene Symbol
SLAMF6
HGNC ID
HGNC:21392
ORF Size (aa)
996
RefSeq ID
NM_052931
RefSeq Synonyms
NM_052931, NM_001184716, NM_001184715, NM_001184714, BC114495, BC113893,
Species
human
UniGene ID
Hs.492348
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.