human RGS20 Over-expression AAV

Name 
AAV-h-RGS20
Cat No 
AAV-221122
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RGS20.

AAV-221122
AAV-h-RGS20

Ready-to-use AAV expressing Human RGS20 (regulator of G-protein signaling 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
g(z)GAP; gz-GAP; RGSZ1; ZGAP1
Description (Vector)
RGS20 belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8601
Gene Name (Vector)
regulator of G-protein signaling 20
Gene Symbol
RGS20
HGNC ID
HGNC:14600
ORF Size (aa)
726
RefSeq ID
NM_003702
RefSeq Synonyms
NM_170587, NM_003702, NM_001286675, NM_001286674, NM_001286673, BC063490, BC015614,
Species
human
UniGene ID
Hs.368733

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.