human RGS20 shRNA silencing AAV

Name
AAV-h-RGS20-shRNA

Cat No
shAAV-221122

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human RGS20.

shAAV-221122

AAV-h-RGS20-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RGS20 (regulator of G-protein signaling 20). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

g(z)GAP; gz-GAP; RGSZ1; ZGAP1

Description (Vector)

RGS20 belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

8601

Gene Name (Vector)

regulator of G-protein signaling 20

Gene Symbol

RGS20

HGNC ID

HGNC:14600

ORF Size (aa)

726

RefSeq ID

NM_003702

RefSeq Synonyms

NM_170587, NM_003702, NM_001286675, NM_001286674, NM_001286673, BC063490, BC015614,

Species

human

UniGene ID

Hs.368733

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.