human RGS20 shRNA silencing Adenovirus

Name 
Ad-h-RGS20-shRNA
Cat No 
shADV-221122
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RGS20.

shADV-221122
Ad-h-RGS20-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RGS20 (regulator of G-protein signaling 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
g(z)GAP; gz-GAP; RGSZ1; ZGAP1
Description (Vector)
RGS20 belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
8601
Gene Name (Vector)
regulator of G-protein signaling 20
Gene Symbol
RGS20
HGNC ID
HGNC:14600
ORF Size (aa)
726
RefSeq ID
NM_003702
RefSeq Synonyms
NM_170587, NM_003702, NM_001286675, NM_001286674, NM_001286673, BC063490, BC015614,
Species
human
UniGene ID
Hs.368733

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.