human PAPSS2 Over-expression AAV

Name
AAV-h-PAPSS2

Cat No
AAV-218203

Availability
4-5 weeks

This is an AAV expressing Human PAPSS2.

AAV-218203

AAV-h-PAPSS2

Ready-to-use AAV expressing Human PAPSS2 (3′-phosphoadenosine 5′-phosphosulfate synthase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATPSK2; BCYM4; SK2

Description (Vector)

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene ID

9060

Gene Name (Vector)

3'-phosphoadenosine 5'-phosphosulfate synthase 2

Gene Symbol

PAPSS2

HGNC ID

HGNC:8604

ORF Size (aa)

1845

ORF Size (bp)

1845 bp

RefSeq ID

NM_004670

RefSeq Synonyms

NM_004670, NM_001015880, BC009894,

Species

human

UniGene ID

Hs.524491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.