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human PAPSS2 shRNA silencing AAV

Name 
AAV-h-PAPSS2-shRNA
Cat No 
shAAV-218203
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PAPSS2.

shAAV-218203
AAV-h-PAPSS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PAPSS2 (3′-phosphoadenosine 5′-phosphosulfate synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ATPSK2; BCYM4; SK2
Description (Vector)
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Gene ID
9060
Gene Name (Vector)
3'-phosphoadenosine 5'-phosphosulfate synthase 2
Gene Symbol
PAPSS2
HGNC ID
HGNC:8604
ORF Size (aa)
1845
ORF Size (bp)
1845 bp
RefSeq ID
NM_004670
RefSeq Synonyms
NM_004670, NM_001015880, BC009894,
Species
human
UniGene ID
Hs.524491

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.