human PAK1IP1 Over-expression AAV

Name 
AAV-h-PAK1IP1
Cat No 
AAV-218152
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PAK1IP1.

AAV-218152
AAV-h-PAK1IP1

Ready-to-use AAV expressing Human PAK1IP1 (PAK1 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA421M1.5; hPIP1; MAK11; p21-activated protein kinase-interacting protein 1; PAK/PLC-interacting protein 1; PAK1-interacting protein 1; PIP1; WD repeat-containing protein 84; WDR84
Description (eCommerce)
PIP1/WDR84 (PAK1IP1) was identified as a p21-activated protein kinase (PAK) interacting protein that functions as a negative regulator of PAK activity and PAK signaling pathways. PIP1/WDR84 (PAK1IP1) contains 5 G beta-like WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation.
Gene ID
55003
Gene Name (eCommerce)
PAK1 interacting protein 1
Gene Name (Vector)
PAK1 interacting protein 1
Gene Symbol
PAK1IP1
HGNC ID
HGNC:20882
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1179
ORF Size (bp)
1179 bp
Protein Name (eCommerce)
p21-activated protein kinase-interacting protein 1
RefSeq ID
NM_017906
RefSeq Synonyms
NM_017906, BC010907,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
PIP1/WDR84 (PAK1IP1) was identified as a p21-activated protein kinase (PAK) interacting protein that functions as a negative regulator of PAK activity and PAK signaling pathways. PIP1/WDR84 (PAK1IP1) contains 5 G beta-like WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation.
UniGene ID
Hs.310231
UniProt ID (eCommerce)
Q9NWT1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.