human KEAP1 Over-expression AAV

Name
AAV-h-KEAP1

Cat No
AAV-212864

Availability
4-5 weeks

This is an AAV expressing Human KEAP1.

AAV-212864

AAV-h-KEAP1

Ready-to-use AAV expressing Human KEAP1 (kelch like ECH associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

INrf2; KLHL19

Description (Vector)

KEAP1 encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Gene ID

9817

Gene Name (Vector)

kelch like ECH associated protein 1

Gene Symbol

KEAP1

HGNC ID

HGNC:23177

ORF Size (aa)

1875

ORF Size (bp)

1875 bp

RefSeq ID

NM_012289

RefSeq Synonyms

NM_203500, NM_012289, BC015945, BC002930, BC002417,

Species

human

UniGene ID

Hs.465870

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.