human IVNS1ABP Over-expression AAV

Name 
AAV-h-IVNS1ABP
Cat No 
AAV-212563
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IVNS1ABP.

AAV-212563
AAV-h-IVNS1ABP

Ready-to-use AAV expressing Human IVNS1ABP (influenza virus NS1A binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARA3; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; FLARA3; HSPC068; influenza virus NS1A-binding protein; kelch-like family member 39; kelch-like protein 39; KLHL39; NCX downstream gene 1; ND1; NS-1; NS1-binding protein; NS1BP; NS1-BP
Description (eCommerce)
NS1-binding protein (NS1-BP) plays a role in cell division and in the dynamic organization of the actin skeleton by functioning as a stabilizer of actin filaments via its association with F-actin through Kelch repeats. NS1-BP may be a component of the cellular splicing machinery with a role in pre-mRNA splicing and may mediate the inhibition of splicing by NS/influenza virus NS1A protein. NS1-BP has also been found to function as modifier of the AHR/Aryl hydrocarbon receptor pathway by increasing the concentration of AHR available to activate transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6YO].
Gene ID
10625
Gene Name (eCommerce)
influenza virus NS1A binding protein
Gene Name (Vector)
influenza virus NS1A binding protein
Gene Symbol
IVNS1ABP
HGNC ID
HGNC:16951
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
Protein Name (eCommerce)
Influenza virus NS1A-binding protein
RefSeq ID
NM_006469
RefSeq Synonyms
NM_006469, BC067739,
Research Areas
Cytoskeleton,Gene Expression,Host-Virus Interactions,Response to Virus,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
NS1-binding protein (NS1-BP) plays a role in cell division and in the dynamic organization of the actin skeleton by functioning as a stabilizer of actin filaments via its association with F-actin through Kelch repeats. NS1-BP may be a component of the cellular splicing machinery with a role in pre-mRNA splicing and may mediate the inhibition of splicing by NS/influenza virus NS1A protein. NS1-BP has also been found to function as modifier of the AHR/Aryl hydrocarbon receptor pathway by increasing the concentration of AHR available to activate transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6YO].
UniGene ID
Hs.497183
UniProt ID (eCommerce)
Q9Y6Y0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.