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human IVNS1ABP shRNA silencing Adenovirus

Name 
Ad-h-IVNS1ABP-shRNA
Cat No 
shADV-212563
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human IVNS1ABP.

shADV-212563
Ad-h-IVNS1ABP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IVNS1ABP (influenza virus NS1A binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ARA3; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3; FLARA3; HSPC068; influenza virus NS1A-binding protein; kelch-like family member 39; kelch-like protein 39; KLHL39; NCX downstream gene 1; ND1; NS-1; NS1-binding protein; NS1BP; NS1-BP
Description (eCommerce)
NS1-binding protein (NS1-BP) plays a role in cell division and in the dynamic organization of the actin skeleton by functioning as a stabilizer of actin filaments via its association with F-actin through Kelch repeats. NS1-BP may be a component of the cellular splicing machinery with a role in pre-mRNA splicing and may mediate the inhibition of splicing by NS/influenza virus NS1A protein. NS1-BP has also been found to function as modifier of the AHR/Aryl hydrocarbon receptor pathway by increasing the concentration of AHR available to activate transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6YO].
Gene ID
10625
Gene Name (eCommerce)
influenza virus NS1A binding protein
Gene Name (Vector)
influenza virus NS1A binding protein
Gene Symbol
IVNS1ABP
HGNC ID
HGNC:16951
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
Protein Name (eCommerce)
Influenza virus NS1A-binding protein
RefSeq ID
NM_006469
RefSeq Synonyms
NM_006469, BC067739,
Research Areas
Cytoskeleton,Gene Expression,Host-Virus Interactions,Response to Virus,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
NS1-binding protein (NS1-BP) plays a role in cell division and in the dynamic organization of the actin skeleton by functioning as a stabilizer of actin filaments via its association with F-actin through Kelch repeats. NS1-BP may be a component of the cellular splicing machinery with a role in pre-mRNA splicing and may mediate the inhibition of splicing by NS/influenza virus NS1A protein. NS1-BP has also been found to function as modifier of the AHR/Aryl hydrocarbon receptor pathway by increasing the concentration of AHR available to activate transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6YO].
UniGene ID
Hs.497183
UniProt ID (eCommerce)
Q9Y6Y0

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.