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mouse IVNS1ABP shRNA silencing Adenovirus

Name 
Ad-m-IVNS1ABP-shRNA
Cat No 
shADV-262500
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Ivns1abp.

shADV-262500
Ad-m-IVNS1ABP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ivns1abp (influenza virus NS1A binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1190004M08Rik; 1700126I16Rik; AA960440; HSPC068; mKIAA0850; ND1; Nd1-L; Nd1-S; NS-1; NS1-BP
Description (Vector)
Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Gene ID
117198
Gene Name (Vector)
influenza virus NS1A binding protein
Gene Symbol
Ivns1abp
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
RefSeq ID
NM_054102
RefSeq Synonyms
NM_054102, NM_001039512, NM_001039511, BC004092,
Species
mouse
UniGene ID
Mm.33764

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.