human INPP5B Over-expression AAV

Name 
AAV-h-INPP5B
Cat No 
AAV-212289
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human INPP5B.

AAV-212289
AAV-h-INPP5B

Ready-to-use AAV expressing Human INPP5B (inositol polyphosphate-5-phosphatase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5PTase
Description (Vector)
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
3633
Gene Name (Vector)
inositol polyphosphate-5-phosphatase B
Gene Symbol
INPP5B
HGNC ID
HGNC:6077
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
RefSeq ID
NM_005540
RefSeq Synonyms
NM_005540, NM_001297434, BC058932,
Species
human
UniGene ID
Hs.449942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.