human INPP5B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human INPP5B.
shADV-212289
Ad-h-INPP5B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human INPP5B (inositol polyphosphate-5-phosphatase B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5PTase
Description (Vector)
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
3633
Gene Name (Vector)
inositol polyphosphate-5-phosphatase B
Gene Symbol
INPP5B
HGNC ID
HGNC:6077
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
RefSeq ID
NM_005540
RefSeq Synonyms
NM_005540, NM_001297434, BC058932,
Species
human
UniGene ID
Hs.449942
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.