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human INPP5B shRNA silencing AAV

Name 
AAV-h-INPP5B-shRNA
Cat No 
shAAV-212289
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human INPP5B.

shAAV-212289
AAV-h-INPP5B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human INPP5B (inositol polyphosphate-5-phosphatase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5PTase
Description (Vector)
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
3633
Gene Name (Vector)
inositol polyphosphate-5-phosphatase B
Gene Symbol
INPP5B
HGNC ID
HGNC:6077
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
RefSeq ID
NM_005540
RefSeq Synonyms
NM_005540, NM_001297434, BC058932,
Species
human
UniGene ID
Hs.449942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.