human IL28B Over-expression AAV

Name 
AAV-h-IL28B
Cat No 
AAV-212167
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IFNL3.

AAV-212167
AAV-h-IL28B

Ready-to-use AAV expressing Human IFNL3 (interferon lambda 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IFN-lambda-3; IFN-lambda-4; IL-28B; IL-28C; IL28B; IL28C
Description (Vector)
IL28B encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Gene ID
282617
Gene Name (Vector)
interferon lambda 3
Gene Symbol
IFNL3
HGNC ID
HGNC:18365
ORF Size (aa)
591
RefSeq ID
NM_172139
RefSeq Synonyms
NM_172139, NM_001346937, BC130316, BC130314,
Species
human
UniGene ID
Hs.406744

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.