mouse IL28B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ifnl3.
shADV-262168
Ad-m-IL28B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ifnl3 (interferon lambda 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IFL-1; IL-28B; Il28; Il28b; INF-alpha; INF-lambda
Description (Vector)
Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Gene ID
338374
Gene Name (Vector)
interferon lambda 3
Gene Symbol
Ifnl3
ORF Size (aa)
582
ORF Size (bp)
582 bp
RefSeq ID
NM_177396
RefSeq Synonyms
NM_177396, BC141644, BC140273,
Species
mouse
UniGene ID
Mm.246799
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.