mouse FOS shRNA Adenovirus

Name 
Ad-m-FOS-shRNA
Cat No 
1835
Availability
Immediate

This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown mouse FOS gene. The shRNA expression is driven by an U6 promoter.

The knockdown of this mouse gene was validated by qPCR in by identity cells.

1835
Ad-m-FOS-shRNA

Ready-to-use mouse FOS shRNA Adenovirus. mouse FOS shRNA adenovirus gene knockdown1835

$995.00
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Product Details

Promoter
U6 ()
Reporter
eGFP
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
c-fos; cFos; D12Rfj1
Description (Vector)
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Gene ID
14281
Gene Name (Vector)
FBJ osteosarcoma oncogene
Gene Symbol
Fos
ORF Size (aa)
1143
ORF Size (bp)
1143 bp
RefSeq ID
NM_010234
RefSeq Synonyms
NM_010234, BC029814,
Species
mouse
UniGene ID
Mm.246513

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.