mouse CLEC4E Over-expression AAV

Name 
AAV-m-CLEC4E
Cat No 
AAV-255643
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Clec4e.

AAV-255643
AAV-m-CLEC4E

Ready-to-use AAV expressing Mouse Clec4e (C-type lectin domain family 4, member e). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C86253; Clecsf9; Mincle
Description (Vector)
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
Gene ID
56619
Gene Name (Vector)
C-type lectin domain family 4, member e
Gene Symbol
Clec4e
ORF Size (aa)
645
ORF Size (bp)
645 bp
RefSeq ID
NM_019948
RefSeq Synonyms
NM_019948, BC003218,
Species
mouse
UniGene ID
Mm.248327

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.