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human CLEC4E shRNA silencing Adenovirus

Name 
Ad-h-CLEC4E-shRNA
Cat No 
shADV-205432
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLEC4E.

shADV-205432
Ad-h-CLEC4E-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLEC4E (C-type lectin domain family 4 member E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLECSF9; MINCLE
Description (Vector)
CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. CLEC4E is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Gene ID
26253
Gene Name (Vector)
C-type lectin domain family 4 member E
Gene Symbol
CLEC4E
HGNC ID
HGNC:14555
ORF Size (aa)
660
ORF Size (bp)
660 bp
RefSeq ID
NM_014358
RefSeq Synonyms
NM_014358, BC000715,
Species
human
UniGene ID
Hs.236516

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.