human NEXN Over-expression AAV

Name 
AAV-h-NEXN
Cat No 
AAV-230087
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NEXN.

AAV-230087
AAV-h-NEXN

Ready-to-use AAV expressing Human NEXN (nexilin F-actin binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMH20; F-actin-binding protein; NELIN; nexilin
Description (eCommerce)
Nexilin is a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC [taken from NCBI Entrez Gene (Gene ID: 91624)].
Description (Vector)
NEXN encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.
Gene ID
91624
Gene Name (eCommerce)
nexilin F-actin binding protein
Gene Name (Vector)
nexilin F-actin binding protein
Gene Symbol
NEXN
HGNC ID
HGNC:29557
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1665
ORF Size (bp)
1665 bp
Protein Name (eCommerce)
Nexilin
RefSeq ID
NM_144573
RefSeq Synonyms
NM_144573, NM_001172309, BC114445, BC114444, BC111395,
Research Areas
Cardiology,Cardiomyopathy,Cardiovascular,Cytoskeleton,Immunology
Research Areas (Faceted)
cardiovascular,cell_biology,immunology
Species
human
Target Sentence
Nexilin is a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC [taken from NCBI Entrez Gene (Gene ID: 91624)].
UniGene ID
Hs.612385
UniProt ID (eCommerce)
Q0ZGT2

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.