human NEXN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NEXN.
shADV-230087
Ad-h-NEXN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NEXN (nexilin F-actin binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMH20; F-actin-binding protein; NELIN; nexilin
Description (eCommerce)
Nexilin is a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC [taken from NCBI Entrez Gene (Gene ID: 91624)].
Description (Vector)
NEXN encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.
Gene ID
91624
Gene Name (eCommerce)
nexilin F-actin binding protein
Gene Name (Vector)
nexilin F-actin binding protein
Gene Symbol
NEXN
HGNC ID
HGNC:29557
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1665
ORF Size (bp)
1665 bp
Protein Name (eCommerce)
Nexilin
RefSeq ID
NM_144573
RefSeq Synonyms
NM_144573, NM_001172309, BC114445, BC114444, BC111395,
Research Areas
Cardiology,Cardiomyopathy,Cardiovascular,Cytoskeleton,Immunology
Research Areas (Faceted)
cardiovascular,cell_biology,immunology
Species
human
Target Sentence
Nexilin is a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC [taken from NCBI Entrez Gene (Gene ID: 91624)].
UniGene ID
Hs.612385
UniProt ID (eCommerce)
Q0ZGT2
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.