human TNFSF18 Over-expression AAV

Name 
AAV-h-TNFSF18
Cat No 
AAV-226109
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNFSF18.

AAV-226109
AAV-h-TNFSF18

Ready-to-use AAV expressing Human TNFSF18 (tumor necrosis factor superfamily member 18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
activation-inducible TNF-related ligand; AITR ligand; AITRL; GITR ligand; GITRL; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; hGITRL; TL6; TNLG2A; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18
Description (eCommerce)
GITR Ligand/TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for receptor TNFRSF18/AITR/GITR and has been shown to modulate T lymphocyte survival in peripheral tissues. GITR Ligand/TNFSF18 is also expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [taken from NCBI Entrez Gene (Gene ID: 8995)].
Description (Vector)
TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Gene ID
8995
Gene Name (eCommerce)
TNF superfamily member 18
Gene Name (Vector)
tumor necrosis factor superfamily member 18
Gene Symbol
TNFSF18
HGNC ID
HGNC:11932
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
534
Protein Name (eCommerce)
Tumor necrosis factor ligand superfamily member 18
RefSeq ID
NM_005092
RefSeq Synonyms
NM_005092, BC112032, BC093986, BC069319,
Research Areas
Apoptosis,Cancer,Immunology,Signal Transduction
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,immunology
Species
human
Target Sentence
GITR Ligand/TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for receptor TNFRSF18/AITR/GITR and has been shown to modulate T lymphocyte survival in peripheral tissues. GITR Ligand/TNFSF18 is also expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [taken from NCBI Entrez Gene (Gene ID: 8995)].
UniGene ID
Hs.248197
UniProt ID (eCommerce)
Q9UNG2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.